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Accutane Side Effects Quadruple Risk of Ulcerative Colitis

The results of a new study found that the side effects of Accutane, an acne drug that is also known as generic isotretinoin, increases the risk of developing inflammatory bowel problems.

The study, conducted by the University of North Carolina Chapel Hill, was published March 30 in the American Journal of Gastroenterology. Researchers say they found that the use of Accutane increased the risk of developing ulcerative colitis by a factor of four.

Researchers looked at data from 87 health insurance plans and found nearly 8,200 people who had been diagnosed with inflammatory bowel disease (IBD), that includes ulcerative colitis and Crohn’s disease.

Researchers found that those taking Accutane were four times more likely to develop ulcerative colitis, and they also determined that the chance of developing the bowel disorder increased in relation to the Accutane dosage, strengthening the evidence of a causal relationship.


Roche faces nearly 1,000 lawsuits over Accutane, which has been associated with bowel problems, depression and birth defects. All of the lawsuits include allegations that Roche failed to adequately warn users about potential Accutane side effects. The company has lost all six cases that have gone to trial so far, with jury awards totaling $56 million.

Accutane recall was issued by Roche in June 2009. Health Canada issued a warning that it has received numerous reports of severe skin reactions, including Stevens-Johnson Syndrome from Accutane.

Stevens-Johnson syndrome (SJS) is a severe skin reaction that occurs as a side effect of several medications.

If you or a family member has been personally injured because of the fault of someone else: by the use of dangerous and defective drugs, bad products, or toxic injury etc then please contact the Dallas Texas Accutane Defective Drugs Product Liability Attorney Dr. Shezad Malik. For a no obligation, free case analysis, please call 214-390-3189 or Contact Me Online.

The Dr. Shezad Malik Law Firm is currently evaluating and accepting Isotretinoin or Accutane Ulcerative Colitis cases.

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